feature
The CAPRISA 004 trial assessed effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide reverse transcriptase inhibitor, for the prevention of HIV acquisition in women. A double-blind, randomized controlled trial was conducted comparing tenofovir gel with placebo gel in sexually active, HIVuninfected18 to 40 year-old women in urban and rural KwaZulu-Natal, South Africa HIV serostatus, safety,sexual behavior and gel and condom use were assessed at monthly follow-up visits for 30 months.
Year of publication:
2010
Theme:
Health and HIV
science.1193748v1[1].pdf
Author:
Quarraisha Abdool Karim, Salim S. Abdool Karim, Janet A. Frohlich, Anneke C. Grobler, Cheryl Baxter, Leila E. Mansoor, Ayesha B.M. Kharsany, Sengeziwe Sibeko, Koleka P. Mlisana, Zaheen Omar, Tanuja N Gengiah, Silvia Maarschalk, Natasha Arulappan, Mukelisiwe Mlotshwa, Lynn Morris, Douglas Taylor, on behalf of the CAPRISA 004 Trial Group
Relevant URL:
Sciencexpress
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